This welcome new edition covers bioprocess engineering principles for the reader with a limited engineering background. It explains process analysis from an engineering point of view, using worked examples and problems that relate to biological systems. Application of engineering concepts is illustrated in areas of modern biotechnology such as recombinant protein production, bioremediation, biofuels, drug development, and tissue engineering, as well as microbial fermentation. The main sub-disciplines within the engineering curriculum are all covered; Material and Energy Balances, Transport Processes, Reactions and Reactor Engineering. With new and expanded material, Doran's textbook remains the book of choice for students seeking to move into bioprocess engineering. New to this edition: all chapters thoroughly revised for current developments, with over 200 pgs of new material, including significant new content in: Metabolic Engineering; Sustainable Bioprocessing; Membrane Filtration; Turbulence and Impeller Design; Downstream Processing; Oxygen Transfer Systems; over 150 new problems and worked examples; and, more than 100 new illustrations.