1. Children’s Tylenol is available as a 160 mg/5mL suspension. However, a parent with a 6- year-old diabetic child with a dye allergy has brought in a prescription for compounding a similar suspension.
Acetaminophen 160 mg/5 mL Sugar-free syrup qs ad 120 mL M.ft. susp. Would you recommend the parent to purchase the OTC product rather than the compounded preparation?
Explain your answer.
2. While preparing the suspension, you notice that the sedimentation rate was too high, what could be done to slow down the rate?
3. Why should the powders be levigated with a small amount of the suspending vehicle prior to bringing the suspension to the desired volume?
4. What can happen to the compounded preparation if the drug powder is not thoroughly "wet" prior to vehicle incorporation?
5. Can the "suspending" agent be used as the wetting agent? Explain your answer.